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Diagnostic yield and safety profile of cryobiopsy in various lung pathologies

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Authors: Sameer Arbat, Ashok Arbat, Swapnil Bakamwar, Parimal Deshpande, Bharat Agrawal, Vinit Niranjane
Publication date : 2019/9/28
Journal : European Respiratory Journal
Volume: 54
Issue : suppl 63
Publisher: European Respiratory Society
Description :
Introduction: 
Cryobiopsy is a relatively new technique used to diagnose lung pathologies. This study focuses on current cryobiopsy techniques, diagnostic yield and complication rates.
Aims and Objective: 
To study the role and to evaluate safety and diagnostic yield of Cryobiopsy in Diffuse Parenchymal Lung Disease (DPLD), peripheral lesions and endobronchial lesions.
Methods:
 It was prospective observational study. All patients with suspected DPLD or with peripheral lung lesion on HRCT and all patients with endobronchial lesion on bronchoscopy were selected and were subjected to cryobiopsy procedure.
Results:
 Out of 83 patients 25 underwent Trans-Bronchial Lung Cryobiopsy (TBLC) for DPLD, 30 underwent TBLC for peripheral lesions and 28 patients were of endo bronchial lesions that underwent Endobronchial Lung Cryobiopsy(EBLC). The results were as shown in Figure 1. Total diagnostic yieald was …

 
 
 

Bronchoscopy safety box and its utility as a barrier in spread of COVID-19 infection

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Authors: Sameer A Arbat, Sweta Raja Chourasia
Publication date : 2021/1/1
Journal : Indian Journal of Respiratory Care
Volume: 10
Issue : 1
Pages : 76
Publisher: Medknow Publications
Description :

Introduction:
The COVID-19 pandemic has infected millions with a high mortality rate. Thousands of frontline health-care workers (HCWs) have been infected with SARS-CoV-2. Protecting HCWs is important.

Aim:

We sought to develop an innovative barrier to prevent COVID-19 virus transmission while performing bronchoscopy and endotracheal intubation.

Settings and Design:

We have designed and developed a barrier called bronchoscopy safety box (BSB).

Materials and Methods:

BSB is made up of acrylic and polyvinyl chloride (PVC) sheets. We have designed two prototypes of BSBs, namely Prototype 1 and Prototype 2. We performed bronchoscopy procedures and intubation procedures with BSBs. Advantages and limitations were noted and analyzed.

Results:

The advantages of BSB include the additional presence of the bronchoscopy aperture and an assistant aperture. All the apertures are covered by …

 
 
 

Guillian–Barre syndrome in COVID-19 pregnancy—first case report

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Authors: Anand S Somkuwar, Dipti Shende, Sameer Arbat, Swapnil Bakamwar
Publication date : 2021/9
Journal : Annals of Indian Academy of Neurology
Volume: 24
Issue : 5
Pages : 804
Publisher: Wolters Kluwer–Medknow Publications
Description :
2. Dubey A, Jain R, Sodani A, Chouksey D. A case of Kennedy’s disease from India. Ann Indian Acad Neurol 2017; 20: 163‑4. 3. Mariotti C, Castellotti B, Pareyson D, Testa D, Eoli M, Antozzi C, et al. Phenotypic manifestations associated with CAG‑repeat expansion in the androgen receptor gene in male patients and heterozygous females: A clinical and molecular study of 30 families. Neuromuscul Disord 2000; 10 (6): 391‑7.

 
 
 

Analyzing the clinical profile of swine flu/influenza A H1N1 infection in central India: a retrospective study

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Authors: Sameer Arbat, Mitesh Dave, Vinit Niranjane, Irfan Rahman, Ashok Arbat
Publication date : 2017/3
Journal : Virusdisease
Volume: 28
Issue : 1
Pages : 33-38
Publisher: Springer India
Description :
Recently, India reported an increase in swine flu (influenza A H1N1) activity. There are limited studies on epidemiology of swine flu in Indian context. This study aims to analyze clinical and epidemiological profile of suspected swine flu cases in central India. 171 cases were included in a hospital based, observational, descriptive study conducted from December 2014 to April 2015. Demographics, clinical presentation and outcome of positive and negative cases were compared. Data was analyzed using STATA software. Distribution by age, sex and residence was found similar (
p > 0.05) in positive and negative cases. Cough (89%), fever (85%) and throat irritation (51%) were chief complaints (avg. duration = 4.9 days). History of travel, history of contact with swine flu cases (p = 0.002) and history of visiting crowded places (p = 0.098) was reported considerably in higher proportion in positive cases as compared to

 
 
 

Purview of allergens through skin test in Central India

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Authors: Ashok Arbat, Sneha Tirpude, Mitesh K Dave, Sukhant Bagdia, Sameer Arbat
Publication date : 2016/7/1
Journal : Environmental Disease
Volume: 1
Issue : 3
Pages : 99
Publisher: Medknow Publications
Description :
Introduction: Clinical history and examination are very important for determining allergy. The most common forms being bronchial asthma (BA) and allergic rhinitis (AR). A lot of patients respond to the primary line of treatment. Patients come forward with the objective of uprooting the cause of these allergies. Skin prick test (SPT) helps in finding the most likely cause after which we can offer them the desensitization and protective advice.

Objective:
To evaluate the performance of various aeroallergens by assessment with SPT in Central India population.
Materials and Methods: One hundred and forty-three patients with BA and AR were subjected to SPT. SPT was performed with antigen extracts from India.
Results: Of the 143 patients, 86 (60%) patients had both BA and AR. These 143 patients showed 454 positive SPT results. Of the 454, 223 (49%) were positive for mites alone. Among the three mites tested for …
 
 
 

Q. What is an Allergy?

Allergies are hypersensitive responses from our immune system to substances that our body comes in contact with. In simpler words, it is an over reaction of our body to otherwise normally harmless substance. A substance that causes an allergic reaction is called an allergen.

Q. What are symptoms of an allergic reaction?

Allergic reactions may occur in the skin, sinuses, airways, eyes, and nasal passages. For example, dust can cause itchy eyes, runny nose, cough. Food allergy can cause vomiting, swelling of the lips, stomach cramps. Insect stings can cause swelling at the site of the sting, wheezing and possible anaphylaxis, which can be life threatening and must be treated as a medical emergency.

Q. What are the common allergens?

Most common allergens are dust mite, pollen grains, wool, animal hair and food products like nuts, corn, shellfish. A research study conducted by KRIMS Hospitals on common allergens in Central India, it was found that 50% of patients from this region had allergy to mite while 20% had allergy to pollen followed by insects, fungus and so on.

 

Q. How is allergy diagnosed?

An allergy specialist will ask the patient questions regarding symptoms, when they occur, how often and if there is a family history. Accordingly an allergy test will be advised. The useful allergy tests include blood IgE levels, Skin Prick Test and Patch Test.

Q. What is the Treatment?

The most effective treatment of an allergy is avoidance of the allergen. Medications used for treatment include antihistamines, local applications, and Immunotherapy, which is also known as hyposensitization. I advise patients to avoid over the counter drugs and consult an allergy specialist for the proper treatment.

*Nagpur will be hosting the “National Conference on Allergy and Asthma”, organized by Department of Pulmonology on 2nd and 3rd March 2019.